Encinitas, CA specialist discusses latest treatment options for psoriatic arthritis
Led by Board-certified Rheumatologist, Dr. Peter Lloyd, Seaside Rheumatology and Wellness Center stays ahead of safe, clinically proven advancements to ease the joint pain, swelling, and stiffness of psoriatic arthritis (PsA). Some of the most exciting innovations in treatment are based on new findings in recent years about PsA’s immune system-related and genetic associations. Here, we discuss the latest treatment for psoriatic arthritis in Encinitas, CA at Dr. Lloyd’s practice.
Targeted biologics
Biologic medications differ from their traditional systemic counterparts that work throughout the body by targeting specific parts of the immune system – not the entire immune system. Biologics for PsA block T-cell immune cells or proteins like interleukin 17-A, 12 and 23 and TNF-alpha inhibitors. These cells and proteins are implicated in the development of both psoriasis and the PsA that affects around one of every four psoriasis sufferers. The IL-12, IL-23, and IL-17 inhibitors are sold under brand names such as Stelara, Skyrizi, and Cosentyx (you have probably seen the commercials). These drugs selectively target proteins associated with inflammation. TNF-alpha inhibitors include Enbrel and Humira. They block the production of TNF-alpha, whose excessive presence among PsA patients leads to fast growth of skin cells, triggers inflammation, and is associated with joint damage. Orencia inhibits the white blood cells (or T-cells) that are activated to produce inflammation.
Systemic treatments
Taken as a pill, injected, or infused, systemics may be prescribed by Dr. Lloyd if you have moderate to severe symptoms of PsA. Additionally, these drugs that work “systemwide” throughout the body may be appropriate among those patients who have not had success with, or who cannot tolerate, other treatments such as topicals and light-based phototherapies. Some of the newer oral medications, for instance, pinpoint the molecules within immune cells. In turn, these drugs modify the complex inflammatory process within these cells to correct overactive immune response. It is this response that produces inflammation manifested as symptoms like tenderness and swelling. Otezla is one example of a newer oral prescription medication that inhibits an enzyme (PDE4), which is responsible for inflammatory action and the level of inflammation associated with PsA. Some oral drugs double as DMARDs (Disease Modifying AntiRheumatic Drugs). DMARDs may be appropriate for PsA patients with severe swelling and pain, as they are designed to slow or stop the progression of the disease and prevent tissue damage.
Multi-faceted treatment
No single therapy may ease your symptoms and slow the disease. For this reason, Dr. Lloyd offers many treatment options. Integrative medicine accounts for the role that lifestyle and diet can play in the progression and severity of PsA symptoms. You may benefit from simple changes, such as introducing supplements such as Omega-3 fatty acids into your routine. These acids have demonstrated a positive impact on the immune system and reducing inflammatory diseases like PsA. A healthy diet and active lifestyle can also help you avoid diseases like type 2 diabetes and heart diseases. If you have psoriatic disease, you are at increased risk of developing these and other medical conditions or comorbidities.
Call 760-509-2429 to schedule your appointment with Dr. Lloyd at Seaside Rheumatology and Wellness Center.
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